Topical ketoprofen plasters (or ketoprofen patches) are designed for localized pain relief, particularly for inflammatory conditions like muscle or joint pain. They should be applied directly to the affected area twice daily, with each plaster lasting approximately 12 hours. The patches are not waterproof, so users should avoid exposing them to water during wear. These patches work by delivering ketoprofen continuously into the tissue beneath the application site, maintaining high local concentrations for therapeutic effects while minimizing systemic side effects. They are considered a simple, effective, and safe option for managing localized painful inflammation.
Key Points Explained:
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Application Frequency and Duration
- Apply 1 plaster to the affected area twice daily (every 12 hours).
- Each plaster remains effective for 12 hours, after which it should be replaced.
- Consistent application ensures continuous drug delivery for optimal pain relief.
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Proper Placement
- Apply directly to the painful or inflamed area (e.g., joints, muscles).
- Ensure the skin is clean and dry before application to improve adhesion.
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Water Resistance
- The patches are not waterproof, so avoid swimming, showering, or excessive sweating while wearing them.
- If the patch loosens due to moisture, replace it with a new one.
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Mechanism of Action
- The patch delivers ketoprofen locally over 24 hours (with twice-daily application), maintaining high tissue concentrations for anti-inflammatory and analgesic effects.
- Systemic absorption is minimal, reducing the risk of side effects like gastrointestinal issues.
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Safety and Efficacy
- Clinical evidence supports its effectiveness for localized pain and inflammation.
- Ideal for patients who prefer non-oral pain relief or have sensitivities to systemic NSAIDs.
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Precautions
- Do not apply to broken or irritated skin.
- Monitor for local skin reactions (e.g., redness, itching) and discontinue if severe.
- Consult a healthcare provider if pain persists beyond a few days.
By following these guidelines, users can maximize the benefits of ketoprofen plasters while minimizing risks. Their targeted action makes them a practical choice for managing localized discomfort without the drawbacks of oral medications.
Summary Table:
| Key Aspect | Guidance |
|---|---|
| Application Frequency | Apply 1 plaster twice daily (every 12 hours). |
| Placement | Apply to clean, dry skin over the painful area (e.g., joints, muscles). |
| Water Resistance | Avoid water exposure (not waterproof); replace if loosened. |
| Mechanism | Delivers ketoprofen locally for 24-hour relief with minimal side effects. |
| Safety Tips | Do not use on broken skin; monitor for reactions. Consult a doctor if needed. |
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