Nitroglycerin transdermal systems come in six standardized sizes, each designed to deliver a specific hourly dose of nitroglycerin. The patch sizes range from 5 cm² to 40 cm², with corresponding delivery rates increasing proportionally from 0.1 mg/hour to 0.8 mg/hour. This tiered system allows healthcare providers to tailor treatment based on patient needs, ensuring precise dosing for conditions like angina pectoris. The clear correlation between patch surface area and drug delivery rate simplifies clinical decision-making while maintaining therapeutic efficacy.
Key Points Explained:
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Available Patch Sizes
Nitroglycerin transdermal patches are manufactured in six distinct sizes:- 5 cm²
- 10 cm²
- 15 cm²
- 20 cm²
- 30 cm²
- 40 cm²
These standardized dimensions accommodate varying dosage requirements while ensuring consistent drug delivery per unit area.
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Dose-Delivery Correlation
Each patch size delivers nitroglycerin at a predictable hourly rate:Patch Size (cm²) Delivery Rate (mg/hour) 5 0.1 10 0.2 15 0.3 20 0.4 30 0.6 40 0.8 The linear relationship between surface area and delivery rate (0.02 mg/hour per cm²) allows for straightforward dose adjustments. -
Clinical Implications
- Smaller patches (5-15 cm²) are typically used for initial therapy or mild symptoms
- Larger patches (20-40 cm²) address sustained or severe angina episodes
- The 12-hour daily wear period standard minimizes tolerance development
Have you considered how this dosing flexibility impacts long-term treatment plans for cardiac patients?
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Purchasing Considerations
When procuring these systems:- Verify shelf life (nitroglycerin degrades over time)
- Prioritize patches with occlusive backings to prevent drug evaporation
- Assess adhesion quality to ensure consistent wear-time compliance
These factors quietly but critically influence therapeutic outcomes in outpatient settings.
Summary Table:
| Patch Size (cm²) | Delivery Rate (mg/hour) |
|---|---|
| 5 | 0.1 |
| 10 | 0.2 |
| 15 | 0.3 |
| 20 | 0.4 |
| 30 | 0.6 |
| 40 | 0.8 |
Need reliable nitroglycerin transdermal systems tailored to your patients' needs?
At Enokon, we specialize in bulk manufacturing of precision-engineered transdermal patches for pharmaceutical distributors and healthcare brands. Our nitroglycerin systems offer:
- Standardized sizing (5-40 cm²) with linear dose delivery
- Occlusive backings to prevent drug evaporation
- Optimized adhesion for 12-hour wear compliance
Leverage our technical expertise for:
✓ Custom R&D for specialized formulations
✓ Scalable production meeting international quality standards
✓ Clinical support for treatment optimization
Contact our team to discuss your procurement requirements or custom development projects.
