Knowledge What is the purpose of lidocaine 5% plasters? Targeted Relief for Neuropathic Pain
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Tech Team · Enokon

Updated 2 weeks ago

What is the purpose of lidocaine 5% plasters? Targeted Relief for Neuropathic Pain

Lidocaine 5% plasters (also known as lidocaine patch 5 percent) are a topical analgesic designed to provide localized relief for neuropathic pain. They work by numbing the affected area through targeted delivery of lidocaine, a local anesthetic, without significant systemic absorption. These plasters are particularly useful for conditions like post-herpetic neuralgia (PHN), diabetic neuropathy, post-surgical nerve pain, and scar-related discomfort. Their adhesive design ensures prolonged contact with the skin, offering sustained pain relief while minimizing side effects associated with oral medications.

Key Points Explained:

  1. Primary Purpose: Localized Neuropathic Pain Relief

    • Lidocaine 5% plasters are specifically formulated to treat peripheral neuropathic pain, such as:
      • Post-herpetic neuralgia (PHN) – nerve pain following shingles.
      • Painful diabetic neuropathy – nerve damage due to diabetes.
      • Post-surgical nerve pain or trauma-related nerve injuries.
      • Scar pain from surgical incisions or burns.
    • The plaster delivers lidocaine directly to the painful area, blocking sodium channels in nerve endings to reduce pain signals.
  2. Mechanism of Action: Targeted Topical Delivery

    • Unlike oral pain medications, the plaster minimizes systemic exposure, reducing risks like drowsiness or gastrointestinal issues.
    • The 5% lidocaine concentration ensures effective numbing without requiring high doses.
    • The adhesive layer allows for up to 12 hours of continuous application, with studies showing improved pain scores and patient satisfaction.
  3. Clinical Applications and Flexibility

    • Used as monotherapy for mild-to-moderate localized pain or as an adjunct to oral medications (e.g., gabapentin) for severe cases.
    • Particularly beneficial for elderly patients or those with medication sensitivities, as it avoids liver metabolism and drug interactions.
  4. Advantages Over Systemic Treatments

    • Fewer systemic side effects (e.g., no risk of addiction, unlike opioids).
    • Non-invasive and easy to apply, improving adherence compared to oral regimens.
    • Suitable for long-term use in chronic conditions like PHN or diabetic neuropathy.
  5. Patient-Centric Benefits

    • Improves daily functioning by reducing pain during movement or touch (allodynia).
    • Studies report high patient satisfaction due to its localized effect and minimal downtime.
  6. Considerations for Purchasers

    • Cost-effectiveness: While unit costs may be higher than oral generics, reduced side effects can lower overall healthcare expenses.
    • Storage and handling: Plasters require room-temperature storage and intact skin for application.
    • Insurance coverage: Often preferred for PHN due to FDA approval, but coverage may vary for off-label uses (e.g., scar pain).

These plasters exemplify how targeted drug delivery can enhance quality of life for patients with chronic pain, blending innovation with practical clinical utility.

Summary Table:

Feature Benefit
Targeted Pain Relief Blocks nerve signals in specific areas without systemic side effects.
12-Hour Adhesion Prolonged pain relief with a single application.
Non-Addictive Safer alternative to opioids for chronic pain management.
Elderly-Friendly Avoids liver metabolism, ideal for patients with medication sensitivities.
Cost-Effective Reduces long-term healthcare costs by minimizing complications.

Need reliable, high-quality lidocaine plasters for your patients or distribution network?

At Enokon, we specialize in bulk manufacturing of FDA-compliant transdermal pain relief patches, including lidocaine 5% plasters. Our expertise in custom R&D ensures formulations tailored to your clinical or commercial needs.

Bulk supply for distributors & brands
Customizable adhesive strength & release profiles
Strict quality control for consistent dosing

Contact our team today to discuss partnership opportunities or request samples!

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