Which Databases Were Searched For Studies On Transdermal Anti-Inflammatory Patches?

The databases searched for studies on transdermal anti-inflammatory patches included Cochrane Central Register of Controlled Trials, EMBASE, MEDLINE, CINAHL, and PubMed. These databases are widely recognized in medical and pharmaceutical research, providing comprehensive coverage of clinical trials, systematic reviews, and peer-reviewed literature. Their inclusion ensures a thorough examination of existing evidence on transdermal patch technologies and their anti-inflammatory applications.

Key Points Explained:

Cochrane Central Register of Controlled Trials (CENTRAL)
- A primary source for randomized controlled trials (RCTs) and systematic reviews.
- Critical for evaluating the efficacy and safety of transdermal anti-inflammatory patches, as it focuses on high-quality clinical evidence.
EMBASE
- A biomedical and pharmacological database with strong coverage of European and international literature.
- Useful for identifying studies on drug delivery systems, including transdermal patch formulations and their pharmacokinetics.
MEDLINE
- Maintained by the U.S. National Library of Medicine, indexing over 5,000 journals.
- Provides access to foundational research on anti-inflammatory agents and transdermal delivery mechanisms.
CINAHL (Cumulative Index to Nursing and Allied Health Literature)
- Focuses on nursing and allied health research, including patient adherence and practical applications of patches.
- Offers insights into real-world usage and patient outcomes.
PubMed
- A free resource with extensive biomedical literature, including preclinical and clinical studies.
- Ensures no relevant studies on transdermal patch technology are overlooked.

These databases collectively provide a robust foundation for evidence-based conclusions about transdermal anti-inflammatory therapies. Their selection reflects a balance between clinical rigor (CENTRAL, MEDLINE), pharmacological depth (EMBASE), and practical healthcare perspectives (CINAHL). For purchasers, this breadth ensures informed decisions about patch efficacy, safety, and usability.

Summary Table:

Database	Key Features	Relevance to Transdermal Patches
Cochrane Central Register of Controlled Trials (CENTRAL)	Focuses on RCTs and systematic reviews	Evaluates efficacy and safety of patches
EMBASE	Strong biomedical and pharmacological coverage	Identifies drug delivery systems and pharmacokinetics
MEDLINE	Indexes 5,000+ journals via U.S. National Library of Medicine	Provides foundational research on anti-inflammatory agents
CINAHL	Nursing and allied health focus	Insights into patient adherence and real-world usage
PubMed	Free, extensive biomedical literature	Ensures no relevant studies are overlooked

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Which databases were searched for studies on transdermal anti-inflammatory patches?

Key Points Explained:

Summary Table:

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