Knowledge How are Lidoderm patches applied and for how long can they be worn? A Guide to Safe & Effective Pain Relief
Author avatar

Tech Team · Enokon

Updated 3 days ago

How are Lidoderm patches applied and for how long can they be worn? A Guide to Safe & Effective Pain Relief

Lidoderm patches are medicated patches containing lidocaine, a local anesthetic, designed to provide localized pain relief by blocking nerve signals. They are primarily used for postherpetic neuralgia (nerve pain after shingles) but are also prescribed off-label for conditions like diabetic neuropathy and chronic back pain. The patches are applied to clean, dry skin at the pain site and can be worn for up to 12 hours per application, with no more than three patches used in a 24-hour period. Their non-invasive, targeted action minimizes systemic side effects and reduces reliance on oral pain medications.

Key Points Explained:

  1. Application Process

    • Lidoderm patches must be applied to clean, dry skin at the site of pain.
    • Ensure the skin is free of cuts, irritation, or lotions to optimize adhesion and drug absorption.
    • The patch should lie flat against the skin without wrinkles to ensure consistent lidocaine delivery.
  2. Wear Time and Frequency

    • Each patch can be worn for up to 12 hours per application.
    • After removal, a new patch should not be reapplied to the same area for at least 12 hours to avoid skin irritation.
    • No more than three patches should be used within a 24-hour period to prevent excessive systemic absorption.
  3. Mechanism of Action

    • Lidocaine in the patch blocks sodium channels in nerve fibers, inhibiting pain signals locally.
    • The controlled release minimizes systemic exposure, making it safer for prolonged use compared to oral analgesics.
  4. Primary and Off-Label Uses

    • Approved use: Postherpetic neuralgia (PHN), a complication of shingles.
    • Off-label uses: Diabetic neuropathy and chronic back pain, though these lack formal FDA approval.
    • Always follow a healthcare provider’s guidance for off-label applications.
  5. Advantages Over Other Pain Relief Methods

    • Non-invasive alternative to injections or oral medications.
    • Reduces reliance on opioids or NSAIDs, which carry risks of addiction or gastrointestinal side effects.
    • Localized action avoids systemic side effects like drowsiness or dizziness.
  6. Safety Precautions

    • Avoid applying to broken or inflamed skin.
    • Do not use with heating pads or tight bandages, as heat may increase lidocaine absorption to unsafe levels.
    • Monitor for allergic reactions (e.g., redness, swelling) and discontinue use if they occur.

Lidoderm patches exemplify how targeted drug delivery can simplify pain management while improving patient comfort. Their structured application protocol ensures efficacy and safety, making them a valuable tool for specific chronic pain conditions.

Summary Table:

Key Aspect Details
Application Apply to clean, dry skin; avoid cuts/lotions. Ensure patch lies flat.
Wear Time Up to 12 hours per patch; max 3 patches/24 hours.
Primary Use Postherpetic neuralgia (PHN). Off-label: diabetic neuropathy, back pain.
Mechanism Lidocaine blocks nerve signals locally, minimizing systemic exposure.
Advantages Non-invasive, reduces opioid/NSAID reliance, fewer side effects.
Safety Tips Avoid broken skin, heat sources, and monitor for allergic reactions.

Need reliable, custom-formulated transdermal patches for your patients or brand?

Enokon specializes in bulk manufacturing of high-quality pain relief patches, including lidocaine-based solutions like Lidoderm. Our expertise in transdermal technology ensures optimal drug delivery, adhesion, and patient comfort. Whether you're a healthcare distributor or a pharmaceutical brand, we offer:

  • Custom R&D for tailored formulations (e.g., varying lidocaine concentrations or additional active ingredients).
  • Scalable production with strict quality control for consistent performance.
  • Regulatory compliance support for faster market entry.

Contact us today to discuss your project or request samples!

Related Products

Herbal Eye Protection Patch Eye Patch

Herbal Eye Protection Patch Eye Patch

This eye protection patch is rich in Chinese herbal essence, according to the principle of traditional Chinese medicine sticking penetration points, Chinese herbs are carefully proportionally refined. Users include children, teenagers to prevent myopia, office workers, etc.; Single-piece packaging is convenient to carry, when the eyes feel uncomfortable, wear an eye mask or eye mask over the eyes, cool and comfortable immediately relieve eye discomfort; It can be used anywhere, on the subway, on the plane, at the office, at school, at home and so on.

Lidocaine Hydrogel Pain Relief Patch for Pain Relief

Lidocaine Hydrogel Pain Relief Patch for Pain Relief

4% Lidocaine hydrogel pain relief patch for targeted neuropathic & joint pain management. Clinically proven 68% pain reduction with 8-hour sustained release. Hypoallergenic & water-resistant.

Capsaicin Chili Medicated Pain Relief Patches

Capsaicin Chili Medicated Pain Relief Patches

Relieve joint and muscle pain. Capsicum Plaster is a plaster applied to aching joints and muscles, aching shoulders and lumbago, broken bones, arthritis, and sprains. It is suitable for all kinds of pain caused by joint muscle pain, sore shoulder and back pain, arthritis and sprain. It is especially suitable for pain and chronic pain caused by various injuries. middle size with 8*13cm.

Hydra Gel Health Care Eye Patch

Hydra Gel Health Care Eye Patch

The eye production patch is designed with hydrogel. According to the principle of acupoint infiltration of eyes, use well-prepared Chinese herbal medicine. The users include children, teenagers to prevent myopia, office worker and so on; The single piece packing is convenient to carry, put an eye patch or eye mask on you eye when the eye feels uncomfortable, cool and comfortable immediately alleviate the eye discomfort; It can be used anywhere, on the subway, on the plane, in the office, at school and at home, etc.

Far Infrared Deep Heat Relief Patches Medicated Pain Relief Patches

Far Infrared Deep Heat Relief Patches Medicated Pain Relief Patches

Far infrared pain relief patch is a new type of pain relief patch for neck pain use, its main principle is to use far infrared to penetrate into the human body to achieve the effect of pain relief,Far infrared rays can relieve pain. After penetrating the human body, far infrared rays will accelerate blood circulation and promote metabolism, thereby eliminating local pain. In addition, far infrared rays can also improve immunity and antioxidant capacity, which has the effect of improving overall health. This product is suitable for pain caused by various soft tissue injuries and sports injuries, such as cervical spondylosis, shoulder periarthritis, lumbar disc herniation, rheumatoid arthritis, etc

Heating Pain Relief Patches for Menstrual Cramps

Heating Pain Relief Patches for Menstrual Cramps

Heating Pain Relief Patches for menstrual cramps – natural, self-heating therapy with herbal extracts. Soothes pain for 8-12 hours, discreet & drug-free. Try now!

Prostate Pain Kidney Health Care Patch for Men

Prostate Pain Kidney Health Care Patch for Men

This product adopts advanced Chinese medicine extraction technology, concentrates herbal essence, regulates male endocrine, promotes metabolism, and has a good effect on relieving male prostatitis, premature ejaculation, impotence, frequent urination, dysuria and other symptoms. Replaced every 12-24 hours

Asthma Cough and Pain Relief Patch for Adults and Kids

Asthma Cough and Pain Relief Patch for Adults and Kids

Cough relief patch adopts advanced and important extraction technology to extract the effective ingredients, and is prepared according to the scientific ratio of ancient Chinese prescriptions. It can be applied to the body acupoints, which can clear the lung and reduce phlegm, relieve cough and relieve asthma. It is suitable for adults and children.

Far Infrared Heat Pain Relief Patches Transdermal Patches

Far Infrared Heat Pain Relief Patches Transdermal Patches

A pain reliever patch containing herbal extract that quickly heats up and relieves pain. Used for various pain conditions caused by joint and muscle pain, shoulder and back pain, fracture pain, frostbite, and sprains, especially suitable for pain caused by various injuries and chronic pain.

Menthol Gel Pain Relief Patch

Menthol Gel Pain Relief Patch

The main effects of pain relief patch include: • Pain relief: For local pain caused by a variety of causes, such as neuropathic pain, musculoskeletal pain, joint pain and postherpetic neuralgia, pain relief gel patch can effectively reduce the level of pain. It can block the transmission of pain signals to achieve analgesic effect. • Easy to use: Compared to oral painkillers, pain relief gel cold compress patches are easier to use. Simply by applying the patch to the skin at the painful site, the drug can be gradually released to continue its analgesic effect, while reducing the side effects such as gastrointestinal discomfort that may be caused by oral medication. • Promote healing: Some ingredients in pain relief patches can promote fibroblast proliferation and migration, speed up the wound healing process, and promote wound healing after mild trauma. Please note that the use should follow the doctor's advice, pay attention to the skin reaction, in case of discomfort, should immediately stop and seek medical attention.size 7*10cm

Icy Hot Menthol Medicine Pain Relief Patch

Icy Hot Menthol Medicine Pain Relief Patch

The main effects of pain relief gel patch include: • Pain relief: For local pain caused by a variety of causes, such as neuropathic pain, musculoskeletal pain, joint pain and postherpetic neuralgia,pain relief patch can effectively reduce the level of pain. It can block the transmission of pain signals to achieve analgesic effect. • Easy to use: Compared to oral painkillers, painkillers are easier to use. Simply by applying the patch to the skin at the painful site, the drug can be gradually released to continue its analgesic effect, while reducing the side effects such as gastrointestinal discomfort that may be caused by oral medication. • Promote healing: Some ingredients in pain relief patches can promote fibroblast proliferation and migration, speed up the wound healing process, and promote wound healing after mild trauma. Please note that the use should follow the doctor's advice, pay attention to the skin reaction, in case of discomfort, should immediately stop and seek medical attention.

Far Infrared Pain Patch Relief Pain Reliever for Back

Far Infrared Pain Patch Relief Pain Reliever for Back

Relieve Back pain /backache and muscle pain. Far infrared pain relief patch is a new type of pain relief patch, its main principle is to use far infrared to penetrate into the human body to achieve the effect of pain relief,Far infrared rays can relieve pain. After penetrating the human body, far infrared rays will accelerate blood circulation and promote metabolism, thereby eliminating local pain. In addition, far infrared rays can also improve immunity and antioxidant capacity, which has the effect of improving overall health. This product is suitable for pain caused by various soft tissue injuries and sports injuries, such as cervical spondylosis, shoulder periarthritis, lumbar disc herniation, rheumatoid arthritis, etc

Far Infrared Knee Pain Patch Heat Patches for Pain Relief

Far Infrared Knee Pain Patch Heat Patches for Pain Relief

Relieve Knee joint and muscle pain. Far infrared knee pain relief patch is a new type of pain relief patch, its main principle is to use far infrared to penetrate into the human body to achieve the effect of pain relief,Far infrared rays can relieve pain. After penetrating the human body, far infrared rays will accelerate blood circulation and promote metabolism, thereby eliminating local pain. In addition, far infrared rays can also improve immunity and antioxidant capacity, which has the effect of improving overall health. This product is suitable for pain caused by various soft tissue injuries and sports injuries, such as cervical spondylosis, shoulder periarthritis, lumbar disc herniation, rheumatoid arthritis, etc

Natural Herbal Wormwood Patch Pain Plaster

Natural Herbal Wormwood Patch Pain Plaster

Natural Herbal Wormwood Patch for pain relief - targets arthritis, muscle aches, and joint stiffness. Breathable, long-lasting, and suitable for all ages. Order now for fast relief!

Heat Relief Capsicum Patch for Lower Back Pain Relief

Heat Relief Capsicum Patch for Lower Back Pain Relief

Relieve joint and muscle pain. Capsicum Plaster is a plaster applied to aching joints and muscles, aching shoulders and lumbago, broken bones, arthritis, and sprains. It is suitable for all kinds of pain caused by joint muscle pain, sore shoulder and back pain, arthritis and sprain. It is especially suitable for pain and chronic pain caused by various injuries. small size with 7*10cm.

Mugwort Wormwood Pain Relief Patch for Neck Pain

Mugwort Wormwood Pain Relief Patch for Neck Pain

Mugwort Wormwood Pain Relief Patch: Natural herbal solution for neck, joint & muscle pain. Non-invasive, long-lasting relief with anti-inflammatory botanicals. Ideal for athletes & chronic pain sufferers.


Leave Your Message