The granisetron skin patch is applied to clean, dry, hairless skin on the upper outer arm or hip, adhering to specific steps for proper placement and adhesion. Key steps include washing hands and the application area, carefully removing protective liners in stages, pressing firmly for secure attachment, and avoiding water/sun exposure during wear. Timing is critical—apply 2 hours before needed effect and remove within 9-12 hours. Proper disposal involves folding used patches sticky-side together and washing hands post-application to prevent accidental exposure.
Key Points Explained:
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Preparation Before Application
- Wash hands and the application site (upper outer arm or hip) with soap and water.
- Ensure skin is clean, dry, and free of cuts, rashes, or irritation. Avoid areas with hair to improve adhesion.
- Open the foil pouch only immediately before use and inspect for damage.
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Step-by-Step Application
- Step 1: Hold the patch with the printed side facing you. Bend it to peel off half of the plastic liner from the sticky side.
- Step 2: Apply the exposed sticky portion to the skin while holding the remaining liner.
- Step 3: Remove the second liner and press the entire patch firmly for 30 seconds to ensure edges adhere.
- Step 4: Wash hands thoroughly after handling to avoid accidental drug transfer.
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Timing and Wear Guidelines
- Apply the patch 2 hours before the desired effect (e.g., chemotherapy-induced nausea prevention).
- Do not wear for more than 9–12 hours daily to avoid overexposure.
- Avoid swimming, saunas, or strenuous activity during wear to prevent detachment.
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Post-Use and Disposal
- Removal: Peel off slowly and fold sticky sides together to prevent accidental contact.
- Disposal: Flush or discard in a lidded trash bin out of reach of children/pets.
- Residue cleanup: Use oil or lotion to remove adhesive traces from skin.
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Safety Considerations
- Do not cut the patch—altering it may affect drug delivery.
- Avoid sunlight/heat on the applied area to prevent irritation or altered absorption.
- Check for allergies or drug interactions before use, especially in pediatric/geriatric patients.
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Troubleshooting Adhesion Issues
- If edges lift, press firmly again or cover with a breathable bandage (if approved by a healthcare provider).
- Replace the patch if it falls off prematurely; do not reapply the same patch.
By following these steps, users can ensure effective delivery of granisetron while minimizing risks of improper use or exposure.
Summary Table:
| Step | Action | Key Consideration |
|---|---|---|
| Preparation | Wash hands and application site (upper arm/hip). Ensure skin is clean/dry. | Avoid hairy, irritated, or damaged skin. Inspect patch for damage before use. |
| Application | Remove liners in stages, press firmly for 30 seconds. | Wash hands after handling to prevent accidental drug transfer. |
| Timing | Apply 2 hours before needed effect; remove within 9–12 hours. | Avoid water/sun exposure during wear to maintain adhesion and drug delivery. |
| Disposal | Fold used patch sticky-side together; discard securely. | Clean residue with oil/lotion. Keep out of reach of children/pets. |
| Troubleshooting | If edges lift, press again or use a breathable bandage (if approved). | Never cut the patch or reuse a detached one. Replace if adhesion fails. |
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