The selegiline transdermal patch is a prescription medication used to treat depression in adults, functioning as a monoamine oxidase inhibitor (MAOI) that helps maintain mental balance. Proper application involves selecting an appropriate skin site (upper chest, back, thigh, or outer arm), ensuring the skin is clean and dry, and applying the patch firmly to avoid wrinkles. It should be replaced every 24 hours at the same time daily, with rotation of application sites to prevent skin irritation. If a patch loosens, it should be pressed back or replaced. Strict adherence to prescription instructions is crucial for safety and effectiveness.
Key Points Explained:
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Purpose and Mechanism
- The Selegiline Transdermal Patch treats depression by inhibiting monoamine oxidase, increasing neurotransmitters like serotonin and dopamine.
- It’s prescribed for adults and requires careful adherence to avoid interactions (e.g., with certain foods or medications).
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Application Steps
- Preparation: Wash hands and clean the application site (upper chest, back, thigh, or outer arm) with soap/water; ensure skin is dry.
- Application: Remove the patch from its pouch, press firmly onto skin, and smooth out wrinkles to ensure adhesion.
- Rotation: Change the patch daily at the same time, rotating sites to minimize skin irritation.
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Usage Guidelines
- Duration: Wear for 24 hours; replace if it falls off (press back or apply a new one).
- Avoidances: Keep away from heat sources (e.g., saunas) to prevent altered drug delivery.
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Safety and Disposal
- Hand Hygiene: Wash hands before/after application to avoid accidental drug transfer.
- Disposal: Fold used patches adhesive-side in and discard safely to prevent misuse.
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Patch Composition
- Layers include a backing (protection), drug reservoir, rate-controlling membrane, and adhesive.
- Penetration enhancers may be included to optimize drug absorption.
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Patient Tips
- Track application times/sites using a calendar.
- Report skin reactions or unusual symptoms (e.g., dizziness) to a doctor promptly.
By following these steps, patients can ensure effective treatment while minimizing risks. The patch’s design allows steady medication delivery, but proper handling is key to its success.
Summary Table:
| Key Aspect | Guidance |
|---|---|
| Application Sites | Upper chest, back, thigh, or outer arm (clean, dry, hair-free skin) |
| Frequency | Replace every 24 hours at the same time; rotate sites to avoid irritation |
| Adhesion | Press firmly; smooth wrinkles. Replace if loose. |
| Precautions | Avoid heat sources (saunas), wash hands before/after use. |
| Disposal | Fold adhesive-side in; discard safely to prevent misuse. |
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