To properly handle transdermal selegiline, you must store the patches at room temperature in their individual protective pouches, away from heat and moisture. For disposal, the safest method is a medicine take-back program; you should never flush patches down the toilet. Crucially, both new and used patches must be kept out of the reach of children and pets at all times.
The core principle for handling selegiline patches is preventing both medication degradation and accidental exposure. Because even used patches contain a significant amount of active drug, proper storage and disposal are critical safety measures, not just recommendations.

Proper Storage: Preserving Medication Integrity
How you store your medication directly impacts its effectiveness. The transdermal delivery system is sensitive to environmental conditions.
Keep at Room Temperature
Store the patches at a controlled room temperature. Avoid places with extreme temperature fluctuations, such as a bathroom (due to steam and humidity) or a car.
Use the Protective Pouch
Each patch comes in a sealed, protective pouch. This pouch shields the medication from air and moisture, which can degrade the selegiline and compromise the adhesive.
Only open a pouch immediately before you are ready to apply the patch.
Ensure a Secure Location
Always store the medication in a place that children and pets cannot access. Accidental ingestion of a patch can be fatal.
Safe Disposal: Preventing Accidental Exposure
Disposing of selegiline patches requires care because a significant amount of the drug remains even after the patch has been used.
The Danger in Used Patches
A used patch can still contain enough selegiline to cause serious harm or death if chewed or ingested by a child or pet. Never leave a used patch where it can be easily found, such as in an open household trash can.
The Recommended Disposal Method
The safest way to dispose of used or unused patches is through a U.S. Drug Enforcement Administration (DEA)-authorized medicine take-back program. These are often located at pharmacies or police stations.
This method ensures the potent medication is handled and destroyed properly, preventing environmental contamination and accidental exposure.
Why You Should Never Flush Patches
Flushing patches introduces the medication into the water supply, which can harm the environment and is not effectively removed by water treatment facilities.
Understanding the Associated Risks
Handling transdermal selegiline correctly involves being aware of its potential dangers beyond storage and disposal.
Risk of Accidental Ingestion
The primary risk is accidental exposure, especially to children and pets. The patch's design can be appealing, but ingestion can lead to a medical emergency. This is the central reason for secure storage and careful disposal.
Skin Irritation
The patch adhesive and medication can cause skin irritation. It is important to apply the patch to a clean, dry, hair-free area of skin and to rotate application sites with each new patch to allow the skin to heal.
Medication Interactions and Diet
Selegiline has critical interactions with many other medications, particularly other antidepressants. It can also require dietary restrictions, as patients on 9 mg or 12 mg patches must avoid tyramine-rich foods to prevent a dangerous hypertensive crisis.
A Simple Checklist for Safe Handling
Use these guidelines to ensure you are managing your treatment safely and effectively.
- If your primary focus is medication effectiveness: Store patches in their original, sealed pouches at room temperature until the moment of application.
- If your primary focus is preventing accidental harm: Always keep both new and used patches out of the sight and reach of children and pets.
- If your primary focus is responsible disposal: Use a designated medicine take-back program as your primary disposal method for all used and expired patches.
Following these handling protocols is a critical part of ensuring your treatment is both safe and effective.
Summary Table:
| Handling Aspect | Key Action | Primary Reason |
|---|---|---|
| Storage | Keep in sealed pouch at room temperature, away from moisture and heat. | Preserves drug integrity and adhesive. |
| Disposal | Use a medicine take-back program; never flush. | Prevents accidental ingestion and environmental harm. |
| Safety | Keep new and used patches out of reach of children and pets. | Prevents life-threatening accidental exposure. |
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