What Is The Active Principle And Dosage In The Topical Ketoprofen Patch? Key Benefits & Usage Explained

The topical ketoprofen patch contains 100mg of ketoprofen as its active principle, designed to deliver therapeutic doses directly to the site of injury through a specialized delivery system. This localized approach minimizes systemic side effects while providing targeted pain relief, making it particularly useful for musculoskeletal conditions like sprains or arthritis.

Key Points Explained:

Active Principle:
- The sole active ingredient in the patch is ketoprofen (100mg), a nonsteroidal anti-inflammatory drug (NSAID) that inhibits prostaglandin synthesis to reduce pain and inflammation.
- Unlike oral NSAIDs, the patch ensures the drug acts locally, avoiding gastrointestinal irritation.
Dosage and Delivery Mechanism:
- Each ketoprofen patches delivers 100mg of ketoprofen via a controlled-release system, maintaining consistent therapeutic levels at the application site.
- The "novel system" mentioned in references likely refers to adhesive matrix technology, which allows sustained drug penetration through the skin over 12–24 hours.
Clinical Advantages:
- Targeted Action: Minimizes systemic absorption, reducing risks like stomach ulcers or kidney strain.
- Convenience: Single daily application (typically 1 patch/24 hours) simplifies adherence compared to oral dosing.
Considerations for Purchasers:
- Storage: Patches should be kept at room temperature to preserve adhesive and drug stability.
- Contraindications: Avoid use on broken skin or in patients with NSAID allergies.
Comparative Insight:
- While oral ketoprofen doses range from 50–200mg daily, the patch’s 100mg dose is optimized for localized efficacy with lower systemic exposure.

This design exemplifies how transdermal technology can enhance drug safety and patient compliance—key factors for healthcare procurement teams evaluating therapeutic options.

Summary Table:

Aspect	Details
Active Principle	100mg ketoprofen (NSAID) for localized pain and inflammation relief.
Dosage & Delivery	Controlled-release system; 1 patch/24 hours for sustained therapeutic levels.
Key Advantages	Targeted action, reduced systemic side effects, convenient application.
Storage	Room temperature to maintain adhesive and drug stability.
Contraindications	Avoid on broken skin or in patients with NSAID allergies.

Looking for reliable, high-quality ketoprofen patches?

Enokon specializes in bulk manufacturing of transdermal patches, including ketoprofen formulations, for healthcare distributors and brands. Our expertise in custom R&D ensures optimal drug delivery, safety, and compliance.

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What is the active principle and dosage in the topical ketoprofen patch? Key Benefits & Usage Explained

Key Points Explained:

Summary Table:

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