The starting dosage of the Selegiline Transdermal Patch is 6 mg per 24 hours, applied daily. It is available in three strengths: 6 mg, 9 mg, and 12 mg per 24 hours. Dosage adjustments can be made by increasing the strength by 3 mg every two weeks, up to a maximum of 12 mg per 24 hours. Proper application involves rotating sites and ensuring adhesion to clean, dry skin.
Key Points Explained:
-
Starting Dosage
- The initial recommended dose is 6 mg per 24 hours, applied once daily.
- This conservative starting point helps minimize side effects while allowing the body to adjust to the medication.
-
Available Strengths
- The patch comes in three incremental strengths:
- 6 mg/24h (starting dose)
- 9 mg/24h (first potential adjustment)
- 12 mg/24h (maximum dose)
- These options provide flexibility for gradual titration based on patient response.
- The patch comes in three incremental strengths:
-
Dosage Adjustment Protocol
- Increases are made in 3 mg increments (e.g., 6 mg → 9 mg).
- Changes should occur no sooner than every two weeks to assess tolerability.
- The maximum dose is 12 mg/24h; exceeding this is not recommended due to safety concerns.
-
Application Guidelines
- Apply to clean, dry skin on approved areas (upper chest, back, thigh, or outer arm).
- Rotate sites to avoid skin irritation.
- Replace the patch every 24 hours for consistent drug delivery.
-
Clinical Considerations
- The patch’s transdermal design bypasses first-pass metabolism, offering steadier drug levels than oral forms.
- Patients should avoid heat exposure (e.g., saunas) to prevent altered drug absorption.
This structured approach balances efficacy with safety, making the Selegiline Transdermal Patch a manageable option for depression treatment. Would gradual titration impact adherence in your patient population?
Summary Table:
| Key Aspect | Details |
|---|---|
| Starting Dosage | 6 mg per 24 hours (applied daily) |
| Available Strengths | 6 mg, 9 mg, 12 mg per 24 hours |
| Dosage Adjustment | Increase by 3 mg every 2 weeks (max: 12 mg/24h) |
| Application | Rotate sites; apply to clean, dry skin (chest, back, thigh, or arm) |
| Clinical Note | Avoid heat exposure to maintain consistent absorption. |
Need reliable transdermal patches for your patients or distribution network?
Enokon specializes in high-quality transdermal drug delivery systems, including custom formulations for depression treatment like selegiline patches. Our expertise ensures:
- Precise dosing (6 mg to 12 mg strengths)
- Optimal adhesion with skin-friendly materials
- Bulk manufacturing for distributors and healthcare brands
Contact our team to discuss tailored solutions or request samples today!
