What should be done if a dose of transdermal selegiline is missed? Follow These Steps for Safe Use

If a dose of the Selegiline Transdermal Patch is missed, the general guidance is to remove the old patch and apply a new one as soon as remembered, then continue with the regular dosing schedule. Never apply an extra patch to make up for the missed dose. If it is almost time for the next scheduled dose, skip the missed one and resume the normal schedule. Consistency in application timing is important for maintaining therapeutic drug levels.

Key Points Explained:

1. Immediate Action Upon Realization

   • If a dose is missed, remove the old patch and apply a new one promptly. Delaying reapplication could disrupt steady drug levels in the body.
   • Example: If the patch was due at 8 AM but noticed at noon, replace it immediately rather than waiting until the next day.

2. Avoid Doubling Up

   • Never apply an additional patch to compensate for the missed dose. Excess medication increases the risk of side effects (e.g., hypertension, dizziness).
   • Rationale: Transdermal delivery systems are designed for controlled release; doubling up can overwhelm this mechanism.

3. Proximity to Next Dose

   • If the missed dose is close to the next scheduled application (e.g., within a few hours), skip the missed dose entirely.
   • Why? This prevents overmedication and aligns with the principle of maintaining consistent intervals (typically 24 hours for selegiline patches).

4. Resuming Regular Schedule

   • After addressing the missed dose, continue applying patches at the original times.
   • Tip: Setting daily reminders can help avoid future lapses, especially since adherence is critical for managing conditions like Parkinson’s or depression.

5. Storage and Handling Reminders

   • Store unused patches at room temperature, away from moisture.
   • Proper handling ensures drug efficacy when reapplying after a missed dose.

By following these steps, users can safely manage missed doses while minimizing risks. For persistent issues, consulting a healthcare provider about adjusting the schedule may be beneficial.

Summary Table:

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