In the event of a suspected rivastigmine patch overdose, immediate action is critical. The first and most important step is to remove any and all rivastigmine patches from the person's body to stop further absorption of the medication. You must then seek immediate medical help and should not apply a new patch for at least 24 hours.
A rivastigmine overdose is a serious medical situation that requires a clear, two-step response. First, physically remove the source of the drug by taking off all patches, and second, contact a poison control center or emergency services without delay.

A Step-by-Step Emergency Protocol
Understanding the correct sequence of actions can significantly impact the outcome of an accidental overdose. The goal is to first halt the exposure and then get professional medical guidance.
Step 1: Immediately Remove All Patches
The most crucial first step is to remove every rivastigmine patch from the skin. An overdose often occurs when a new patch is applied without removing the old one.
Carefully peel off any patches you find. This action immediately stops the body from absorbing more of the drug.
Step 2: Seek Immediate Medical Help
After removing the patches, you must contact medical professionals. The service you call depends on the severity of the symptoms.
For severe symptoms like the person collapsing, having a seizure, experiencing trouble breathing, or being unable to be awakened, call 911 or your local emergency services immediately.
For all other suspected overdose situations, even if symptoms seem mild, call your local poison control center right away. They are equipped to provide expert guidance for this specific situation.
Step 3: Do Not Reapply for 24 Hours
After an overdose event, do not apply any additional patches for the next 24 hours. This allows the excess medication in the body to be processed and reduces the risk of worsening symptoms. A doctor will provide guidance on when it is safe to resume treatment.
Recognizing the Symptoms of Overdose
Being able to identify the signs of an overdose is key to acting quickly. Symptoms can range from mild discomfort to life-threatening events.
Common Physical Symptoms
These signs indicate that the body is reacting to an excessive amount of the medication.
- Nausea, vomiting, or diarrhea
- Increased saliva or sweating
- Slow heartbeat
- Dizziness or muscle weakness
- Headache
Severe, Life-Threatening Symptoms
The following are signs of a medical emergency that require immediate intervention from emergency services.
- Difficulty breathing
- Fainting or collapsing
- Seizures
- Inability to be awakened
Common Pitfalls and Prevention
The most effective way to manage an overdose is to prevent one from happening. Understanding the risks associated with patch therapy is essential for patient and caregiver safety.
The Danger of Multiple Patches
The primary cause of overdose is "patch stacking"—applying a new patch while forgetting to remove the previous day's patch. Always establish a routine to locate and remove the old patch before applying a new one.
The Risk of Accidental Exposure
A patch that is chewed, swallowed, or handled improperly can also lead to overdose. If a patch is accidentally ingested, try to remove it from the mouth if possible and seek emergency medical help immediately.
How to Safely Handle and Dispose of Patches
Always wash your hands thoroughly after handling a patch to avoid transferring medication to your eyes or to others.
When disposing of a used patch, fold it in half with the sticky, medicated sides pressed together. This prevents accidental exposure to any remaining medication in the patch.
Making the Right Choice for Patient Safety
Your response should be dictated by the seriousness of the situation you observe.
- If the person has collapsed, is having a seizure, or has trouble breathing: Call 911 or your local emergency services immediately.
- If the person is conscious but showing other overdose symptoms: Remove all patches from their body and call your local poison control center for guidance.
- To prevent future incidents: Always remove the old patch before applying a new one and dispose of used patches safely by folding them in half.
Following these clear protocols is the most effective way to ensure patient safety and manage the risks associated with rivastigmine therapy.
Summary Table:
| Action | Key Step | Who to Contact |
|---|---|---|
| Step 1 | Immediately remove all patches from the skin. | N/A |
| Step 2 | Seek immediate medical help based on symptoms. | 911 for severe symptoms (e.g., seizures, trouble breathing); Poison Control for other cases. |
| Step 3 | Do not reapply a patch for at least 24 hours. | Follow a doctor's guidance for resuming treatment. |
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