Methylphenidate transdermal is currently available in a single dosage form - an extended-release transdermal patch (film) system. This delivery method provides controlled medication release through the skin over an extended period. The available dosage strengths are specifically designed for 9-hour wear time, offering flexibility in dosing based on individual patient needs and response to therapy.
Key Points Explained:
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Dosage Form Availability
- Methylphenidate transdermal is exclusively formulated as an extended-release transdermal patch system
- No other dosage forms (such as gels, creams, or immediate-release patches) are currently available for methylphenidate transdermal delivery
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Available Strengths & Duration
- The system comes in four standardized dosage options:
- 10 mg designed for release over 9 hours
- 15 mg designed for release over 9 hours
- 20 mg designed for release over 9 hours
- 30 mg designed for release over 9 hours
- All versions share the same 9-hour wear time, with differences being in the total drug content and release rate
- The system comes in four standardized dosage options:
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Product Characteristics
- The patch is a drug-in-adhesive matrix system where methylphenidate is incorporated into the adhesive layer
- Designed for once-daily application (typically in the morning)
- Provides continuous medication delivery through the skin
- Removal after 9 hours helps minimize potential sleep disturbances
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Usage Considerations
- Applied to clean, dry, hairless skin (typically on the hip area)
- Should be pressed firmly for proper adhesion
- Rotate application sites to prevent skin irritation
- Not to be cut or altered in any way
- Missed dose protocol: apply when remembered but remove at scheduled time
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Therapeutic Context
- Approved for treatment of Attention Deficit Hyperactivity Disorder (ADHD)
- Transdermal delivery offers advantages for patients who have difficulty swallowing pills
- Provides more consistent blood levels compared to some oral formulations
- May have different side effect profile compared to oral methylphenidate products
When considering this product for clinical use or procurement, it's important to note that the transdermal system represents a specialized delivery method that requires proper patient education about application technique, wear time, and disposal. The fixed 9-hour wear time makes it particularly suitable for daytime symptom control in ADHD patients.
Summary Table:
| Key Feature | Details |
|---|---|
| Dosage Form | Extended-release transdermal patch (film) system |
| Available Strengths | 10 mg, 15 mg, 20 mg, 30 mg (all designed for 9-hour wear time) |
| Application | Once-daily, applied to clean, dry, hairless skin (typically hip area) |
| Duration | 9-hour continuous medication delivery |
| Therapeutic Use | Treatment of ADHD, ideal for patients with difficulty swallowing pills |
| Special Considerations | Rotate application sites, do not cut or alter, remove after 9 hours |
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