The generic name and dosage form of the transdermal medication discussed vary depending on the specific drug. Common examples include granisetron (3.1 mg/24 hr transdermal film, extended release), clonidine (0.1 mg/24 hr, 0.2 mg/24 hr, and 0.3 mg/24 hr extended-release transdermal film), selegiline (6 mg/24 hr, 9 mg/24 hr, and 12 mg/24 hr extended-release transdermal film), and estradiol (available in gel, spray, and patch forms with varying strengths). These medications are designed for sustained drug delivery through the skin, offering an alternative to oral administration.
Key Points Explained:
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Granisetron Transdermal Medication
- Generic Name: Granisetron
- Dosage Form: Extended-release transdermal patch
- Strength: 3.1 mg/24 hr
- Purpose: Primarily used to prevent nausea and vomiting caused by chemotherapy.
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Clonidine Transdermal Medication
- Generic Name: Clonidine
- Dosage Form: Extended-release transdermal film
- Strengths: 0.1 mg/24 hr, 0.2 mg/24 hr, and 0.3 mg/24 hr
- Purpose: Used to treat high blood pressure and sometimes ADHD or menopausal hot flashes.
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Selegiline Transdermal Medication
- Generic Name: Selegiline
- Dosage Form: Extended-release transdermal film
- Strengths: 6 mg/24 hr, 9 mg/24 hr, and 12 mg/24 hr
- Purpose: Used to treat major depressive disorder (MDD) by inhibiting monoamine oxidase.
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Estradiol Transdermal Medication
- Generic Name: Estradiol
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Dosage Forms:
- Gel: 0.06% and 0.1%
- Spray: 1.53 mg topical spray
- Patch: 0.014 mg, 0.025 mg, 0.0375 mg, 0.05 mg, 0.06 mg, 0.075 mg, and 0.1 mg
- Purpose: Hormone replacement therapy for menopausal symptoms.
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General Characteristics of Transdermal Medications
- Administration: Applied to the skin for systemic absorption.
- Advantages: Avoids first-pass metabolism, provides sustained release, and improves patient compliance.
- Common Forms: Patches, films, gels, and sprays.
These medications are tailored for specific therapeutic needs, offering flexibility in dosing and administration. Have you considered how the extended-release feature of transdermal films enhances patient convenience compared to oral medications? This technology quietly revolutionizes treatment adherence in chronic conditions.
Summary Table:
| Medication | Generic Name | Dosage Form | Strengths | Primary Use |
|---|---|---|---|---|
| Granisetron | Granisetron | Extended-release transdermal film | 3.1 mg/24 hr | Prevents nausea/vomiting from chemotherapy |
| Clonidine | Clonidine | Extended-release transdermal film | 0.1 mg/24 hr, 0.2 mg/24 hr, 0.3 mg/24 hr | Treats hypertension, ADHD, or menopausal hot flashes |
| Selegiline | Selegiline | Extended-release transdermal film | 6 mg/24 hr, 9 mg/24 hr, 12 mg/24 hr | Treats major depressive disorder (MDD) |
| Estradiol | Estradiol | Gel, spray, or patch | Gel: 0.06%, 0.1%; Spray: 1.53 mg; Patch: 0.014 mg–0.1 mg | Hormone replacement for menopausal symptoms |
| All | – | Skin-applied (patch/film/gel/spray) | Sustained systemic delivery | Avoids first-pass metabolism, improves compliance, ideal for chronic conditions |
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